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. Since the emergence of COVID-19 delta mutant (Delta) in India in 2020, it has spread in more than 130 countries and regions around the world. Aiming at the virus with high viral load, short incubation period and rapid propagation, all parties are working hard to promote vaccine research and development. On p>

8 5, the Kangtai biotech (300601.SZ) company announced that the company has made important progress in the vaccine research and development project of COVID-19 mutant, and has successfully isolated a variety of strains from the delta strain. p> < p > in fact, Kexing and Zhongsheng, the first two new crown inactivated vaccine companies to enter conditional listing in China, have also carried out vaccine research and development of delta mutant strain < p > "in the near future, Kexing will also submit applications for clinical research and emergency use of Kelaifu of gamma strain and Kelaifu of delta strain to national drug administrations“ On August 5, Yin Weidong, chairman of Kexing holding Biotechnology Co., Ltd., disclosed to China first finance and economics < p > Zhongsheng group also promoted the research and development of inactivated vaccines against multiple mutant strains. It is reported that Zhongsheng's research and development of inactivated vaccine against beta variant strain is in progress and is currently in the stage of animal experiment. Inactivated vaccines against delta mutants are also under development. In other technical routes, the research and development of recombinant protein vaccine and mRNA vaccine for mutant strains are also in progress < p > "for the inactivated vaccine of delta variant strain, we recently submitted (Clinical Research) application." Zhang Yuntao, vice president of China Biotechnology Co., Ltd., told first finance

Novel coronavirus pneumonia was reported in the press conference of the State Council joint prevention and control mechanism in August 5th. He Qinghua, the first inspector of the National Health Protection Committee, said that the delta strain was first discovered in the new crown pneumonia case reported in India in September 2020. The WHO announced in May 10th this year that the variant of Del tower should be included in the new crown virus variant that the world needs to be concerned about. At present, it has been prevalent in more than 130 countries and regions, and has become the main virus strain of the global new crown pandemic. The virus strain has the characteristics of rapid transmission, rapid replication in vivo, long negative time and so on

but He Qinghua also said that the relevant scientific research and epidemic prevention and control practice at home and abroad showed that the delta strain did not lead to disruptive changes in the biological characteristics of COVID-19. The sources and routes of transmission were basically clear. The existing epidemic prevention and control measures are still effective for the mutant strain of Delta. The existing vaccines still have good preventive and protective effects, can reduce the risk of virus transmission in the population, reduce the transmission power of infected people, and effectively reduce the incidence and mortality of severe cases after infection < p > according to some research data, the current new crown inactivated vaccine is still effective for delta variant strain

7 20, a research institute in Sri Lanka released a study on the effectiveness of China's new China biological crown vaccine, which shows that the vaccine is similar to the current variant of the delta strain and beta antibody, which is similar to that of natural infection after vaccination. The antibody neutralization activity of the new Chinese biological crown inactivated vaccine against the delta variant virus found at present decreased by about 1.38 times (down 32%), that is, after two injections of the inactivated Chinese biological vaccine, the protection rate against the popular delta variant virus is still 68%. The new Chinese biological crown vaccine still has good protective effect against delta strain < p > but it should not be ignored that delta mutant has also caused breakthrough infection cases in many countries

in July 30th, the CDC (US Centers for Disease Control and prevention) released the "incidence rate and Mortality Weekly (MMWR)". The delta virus infection caused the same high viral load of COVID-19 in vaccinated and unvaccinated people. The high viral load indicates an increased risk of transmission and raises concerns that, unlike other variants, vaccinators infected with delta virus can transmit the virus. The study found that 274 (79%) vaccinated patients with breakthrough infection developed symptoms < p > because of this, the race against the mutant strain has also become the main task of vaccine research and development < p > < p > according to the information from Kexing, Zhongwei of Kexing isolated the gamma variant strain in December 2020 and the delta variant strain in April, and put it into the action of changing the strain of the new crown inactivated vaccine < p > "in fact, the research on the replacement of inactivated vaccine strains has been carried out all the time. However, in the first half of the year, it was not in a hurry to replace the inactivated vaccine strains because it was not clear which would become the main epidemic strains. The work of changing virus strains can only be carried out after judging the trend of epidemic virus strains. However, due to sufficient preparatory work, once the mainstream strain is found, it can be replaced at any time. " An epidemiologist said < p > according to Yin Weidong, ZTE has sufficient production capacity to provide different kinds of new crown inactivated vaccines
2023-03-22 10:04:40